Accurate Determination of Phenotypic Information from Historic Thoroughbred Horses by Single Base Extension
نویسندگان
چکیده
Historic DNA data have the potential to identify phenotypic information otherwise invisible in the historical, archaeological and palaeontological record. In order to determine whether a single nucleotide polymorphism typing protocol based on single based extension (SNaPshot™) could produce reliable phenotypic data from historic samples, we genotyped three coat colour markers for a sample of historic Thoroughbred horses for which both phenotypic and correct genotypic information were known from pedigree information in the General Stud Book. Experimental results were consistent with the pedigrees in all cases. Thus we demonstrate that historic DNA techniques can produce reliable phenotypic information from museum specimens.
منابع مشابه
Frequency of Limb Injuries Between Thoroughbred and Arabian Horses
This study aimed to investigate the relationship between race horse breed and the frequency of limb injuries through the time of training and racing. The study population consisted of 4042 Thoroughbred and 2553 Arabian horses raced at Warsaw race Track, from 2000 to 2008. Among these horses, 94 Thoroughbreds and 32 Arabians had different limb injuries. Based on the achieved results, it is possi...
متن کاملThe Comparative Analysis of the Allele Pool of Thoroughbred Horses in Different Countries
The aim of the present study was the conducting of comparative analysis of allele pool of Ukrainian population of Thoroughbred horses and the populations from England, USA, Russia and South Korea using microsatellite loci of DNA on the basis of our own researches and literary sources. Comparative analysis of allele pool of Thoroughbred populations from different countries was conducted using 6 ...
متن کاملGrowth Rate of Thoroughbred Horses during First Six Months of Life
The aim of this study was to analyze the effect of sex, season and year of birth on growth rate of biometric measurements and body weight gain of Thoroughbred foals during first six months of life. 103 Thoroughbred foals (53 colts and 50 fillies) from Golejewko Stud born between 2006 and 2008, were used in this study. Thoroughbred foals born in winter months were characterized by significantly ...
متن کاملMissense Mutation in the Ligand-Binding Domain of the Horse Androgen Receptor Gene in a Thoroughbred Family with Inherited 64,XY (SRY+) Disorder of Sex Development.
Disorders of sex development (DSD) have long been documented in domestic animal species including horses. However, there is only a single report of an androgen receptor (AR) mutation causative of such a DSD syndrome in a horse pedigree. Here, we present a new familial AR mutation in horses. A missense mutation (c.2042G>C) at AR exon 4 explains the segregation of the DSD in a Thoroughbred horse ...
متن کاملA comparative antibody study of the potential susceptibility of Thoroughbred and non‐Thoroughbred horse populations in Ireland to equine influenza virus
BACKGROUND In Ireland, horses may be protected against equine influenza virus (EIV) as a result of natural exposure or vaccination. Current mandatory vaccination programmes are targeted at highly mobile horses. A correlation between antibody levels as measured by single radial haemolysis (SRH) and protective immunity against EIV has been established. OBJECTIVES The objective of this study was...
متن کامل